Mayo Clinic Health Library

Taking meds? Hold the grapefruit juice

Updated: 09-15-2012

Grapefruit juice can alter the effects of several kinds of drugs, including statins (taken for high cholesterol), some antidepressants and blood pressure medications. The same goes for whole grapefruit and any grapefruit products, as well as pomelos, Seville oranges and products made with these fruits. Don't take medication with grapefruit products unless your doctor or pharmacist says it's OK.