Mayo Clinic Health Library

Question

Latent autoimmune diabetes in adults (LADA): What is it?

I've been diagnosed with LADA — latent autoimmune diabetes in adults. What's the difference between it and other forms of diabetes?

Updated: 08-14-2013

Answer

Latent autoimmune diabetes in adults (LADA) is a slow progressing form of autoimmune diabetes. Like type 1 diabetes, LADA occurs because your pancreas stops producing adequate insulin, most likely from some "insult" that slowly damages the insulin-producing cells in the pancreas. But unlike type 1 diabetes, with LADA, you often won't need insulin for several months up to years after you've been diagnosed.

Many researchers believe LADA, sometimes called type 1.5 diabetes, is a subtype of type 1 diabetes. Other researchers believe diabetes occurs on a continuum, with LADA falling between type 1 and type 2 diabetes.

People diagnosed with LADA are usually over age 30. Because they're older when diagnosed than is typical for someone with type 1 diabetes and because initially their pancreases still produce some insulin, people with LADA are often misdiagnosed with type 2 diabetes.

At first, LADA can be managed by controlling your blood glucose with diet, weight reduction if appropriate, exercise and, possibly, oral medications. But as your body gradually loses its ability to produce insulin, insulin shots will eventually be needed.

If you've been diagnosed with type 2 diabetes and you're lean and physically active or have recently lost weight without effort, talk with your doctor about whether your current treatment is still the best one for you.

More research is needed before the best way to treat LADA is established. If you've been diagnosed with LADA, talk with your doctor about your best treatment options. As with any type of diabetes, you'll need close follow-up to minimize progression of your diabetes and potential complications.