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Mayo Clinic Health Library

Poison ivy rash

Updated: 10-17-2020

Overview

Poison ivy rash is caused by an allergic reaction to an oily resin called urushiol (u-ROO-she-ol). This oily resin is in the leaves, stems and roots of poison ivy, poison oak and poison sumac.

Wash your skin right away if you come into contact with this oil, unless you know you're not sensitive to it. Washing off the oil may reduce your chances of getting a poison ivy rash. If you develop a rash, it can be very itchy and last for weeks.

You can treat mild cases of poison ivy rash at home with soothing lotions and cool baths. You may need prescription medication for a rash that's severe or widespread, especially if it's on your face or genitals.

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Symptoms

Signs and symptoms of a poison ivy rash include:

  • Redness
  • Itching
  • Swelling
  • Blisters
  • Difficulty breathing, if you've inhaled the smoke from burning poison ivy

Poison ivy rash often appears in a straight line because of the way the plant brushes against your skin. But if you develop a rash after touching a piece of clothing or pet fur that has urushiol on it, the rash may be more spread out. You can also transfer the oil to other parts of your body with your fingers. The reaction usually develops 12 to 48 hours after exposure and lasts two to three weeks.

The severity of the rash depends on the amount of urushiol that gets on your skin.

When to see a doctor

Seek emergency medical attention if:

  • You inhaled the smoke from burning poison ivy and are having difficulty breathing

See your doctor if:

  • The reaction is severe or widespread
  • Your skin continues to swell
  • The rash affects your eyes, mouth or genitals
  • Blisters are oozing pus
  • You develop a fever greater than 100 F (37.8 C)
  • The rash doesn't get better within a few weeks
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Causes

Poison ivy rash is caused by an allergic reaction to an oily resin called urushiol. It's found in poison ivy, poison oak and poison sumac. This oily resin is very sticky, so it easily attaches to your skin, clothing, tools, equipment and pet's fur. You can get a poison ivy reaction from:

  • Touching the plant. If you touch the leaves, stem, roots or berries of the plant, you may have a reaction.
  • Touching contaminated objects. If you walk through some poison ivy and then later touch your shoes, you might get urushiol on your hands. You might then transfer it to your face or body by touching or rubbing. If the contaminated object isn't cleaned, the urushiol on it can still cause a skin reaction years later.
  • Inhaling smoke from the burning plants. Even the smoke from burning poison ivy, poison oak and poison sumac can irritate or harm your nasal passages or lungs.

Pus that oozes from blisters doesn't contain urushiol and won't spread the rash. But it's possible to get poison ivy rash from someone if you touch plant resin that's still on the person or contaminated clothing.

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Risk factors

Your risk of a rash is increased if you participate in outdoor activities that put you at higher risk of exposure to poison ivy, poison oak and poison sumac:

  • Cable or telephone line installation
  • Camping
  • Construction
  • Farming
  • Firefighting
  • Fishing from the shoreline
  • Forestry
  • Gardening
  • Hiking
  • Hunting
  • Landscaping
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Complications

If you scratch a poison ivy rash, bacteria under your fingernails may cause the skin to become infected. See your doctor if pus starts oozing from the blisters. Your doctor might prescribe antibiotics. Serious difficulty breathing and inflammation of the lining of the lungs may result from inhaling urushiol.

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Prevention

To prevent poison ivy rash, follow these tips:

  • Avoid the plants. Learn how to identify poison ivy, poison oak and poison sumac in all seasons. When hiking or engaging in other activities that might expose you to these plants, try to stay on cleared pathways. Wear socks, pants and long sleeves when outdoors. If camping, make sure you pitch your tent in an area free of these plants.

    Keep pets from running through wooded areas so that urushiol doesn't stick to their fur, which you then may touch.

  • Wear protective clothing. If needed, protect your skin by wearing socks, boots, pants, long sleeves and heavy gloves.
  • Remove or kill the plants. Identify and remove poison ivy, poison oak and poison sumac from your yard or garden. You can get rid of such plants by applying an herbicide or pulling them out of the ground, including the roots, while wearing heavy gloves. Afterward remove the gloves carefully and wash them and your hands. Don't burn poison ivy or related plants because the urushiol can be carried by the smoke.
  • Wash your skin or your pet's fur. Within 30 minutes after exposure to urushiol, use soap and water to gently wash off the harmful resin from your skin. Scrub under your fingernails too. Even washing after an hour or so can help reduce the severity of the rash.

    If you think your pet may be contaminated with urushiol, put on some long rubber gloves and give your pet a bath.

  • Clean contaminated objects. If you think you've come into contact with poison ivy, wash your clothing promptly in warm soapy water — ideally in a washing machine. Handle contaminated clothing carefully so that you don't transfer the urushiol to yourself, furniture, rugs or appliances.

    Also wash as soon as possible any other items that came in contact with the plant oil — such as outdoor gear, garden tools, jewelry, shoes and even shoelaces. Urushiol can remain potent for years. So if you put away a contaminated jacket without washing it and take it out a year later, the oil on the jacket may still cause a rash.

  • Apply a barrier cream. Try over-the-counter skin products that are intended to act as a barrier between your skin and the oily resin that causes poison ivy rash.
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Diagnosis

You generally won't need to see your doctor to be diagnosed with a poison ivy rash. If you go to a clinic, your doctor will likely diagnose your rash by looking at it. You usually won't need further testing.

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Treatment

Poison ivy treatments usually involve self-care methods at home. And the rash typically goes away on its own in two to three weeks.

If the rash is widespread or causes many blisters, your doctor may prescribe an oral corticosteroid, such as prednisone, to reduce swelling. If a bacterial infection has developed at the rash site, your doctor might prescribe an oral antibiotic.

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Lifestyle and home remedies

A poison ivy rash will eventually go away on its own. But the itching can be hard to deal with and make it difficult to sleep. If you scratch your blisters, they may become infected. Here are some steps you can take to help control the itching:

  • Apply an over-the-counter cortisone cream or ointment (Cortizone 10) for the first few days.
  • Apply calamine lotion or creams containing menthol.
  • Take oral antihistamines, such as diphenhydramine (Benadryl), which may also help you sleep better. An over-the-counter antihistamine that won't make you so drowsy is loratadine (Alavert, Claritin, others).
  • Soak the affected area in a cool-water bath that has about a half cup (100 grams) of baking soda or an oatmeal-based bath product (Aveeno) in it.
  • Place cool, wet compresses on the affected area for 15 to 30 minutes several times a day.
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Preparing for an appointment

You probably won't need medical treatment for a poison ivy rash unless it spreads widely, persists for more than a few weeks or becomes infected. If you're concerned, you'll probably first see your primary care doctor. He or she might refer you to a doctor who specializes in skin disorders (dermatologist).

What you can do

Before your appointment, you may want to list all the medications, supplements and vitamins you take. Also, list questions you'd like to ask your doctor about your poison ivy rash. Examples include:

  • How long will this rash last?
  • Is it contagious?
  • Is it OK to scratch?
  • Will scratching spread the rash?
  • Will popping the blisters spread the rash?
  • What treatments are available, and which do you recommend?
  • What can I do to help control the itching?
  • If the rash doesn't go away or gets worse, when do you think I need to make another appointment with you?
  • How can I prevent this in the future?

What to expect from your doctor

Your doctor is likely to ask you a number of questions, such as:

  • When did you begin experiencing symptoms?
  • Have you had a similar rash in the past?
  • Have you spent time outdoors recently?
  • What treatment steps have you already tried?
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