A031803 |
The purpose of this study is to determine the effectiveness of intravesical gemcitabine in combination with prembrolizumab. Patients must have been diagnosed with invasive bladder and already received chemo. |
Cancer |
Bladder |
AALL08B1 |
Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) |
Childhood Cancers |
Leukemia |
AALL0932 |
Treatment of Patients with Newly Diagnosed Standard Risk B-Precursor Acute Lymphoblastic Leukemia (ALL) |
Childhood Cancers |
Leukemia |
AALL1231 |
A Phase lll Randomized Trial Investigating Bortezomib (NSC#681239; IND# 58443) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T-Lymphoblastic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LLy) |
Childhood Cancers |
Leukemia |
AALL1521 |
A Phase 2 study of the JAK1/JAK2 Inhibitor Ruxolitinib with Chemotherapy in Children with De Novo High-Risk CRLF2 Rearranged and/ or JAK Pathway-Mutant Acute Lymphoblastic Leukemia |
Childhood Cancers |
Leukemia |
Acoustic Diagnosis of Gastroesophageal Reflux Disease |
|
Baby/Child |
Reflux Disease |
ANBL1232 |
Utilizing Response-and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High Risk Neuroblastoma |
Childhood Cancers |
Blastoma |
APEC14B1 EveryChild |
A Registry, Eligibility Screening, Biology and Outcome Study |
Childhood Cancers |
Registry |
Bayer ON-TRK |
The purpose of this study is to learn about the effectiveness of Vitrakvi in patients with TRK Fusion cancer. You must have a advanced solid tumor with a NTRK gene fusion. |
Cancer |
All tumor types |
Champion AF |
The primary objective of this study is to determine if left atrial appendage closure with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in patients with non-valvular atrial fibrillation. |
Heart & Vascular |
Atrial Fibrillation |
COG-AALL05B1 |
Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens |
Childhood Cancers |
Leukemia |
COG-AALL1331 |
Risk Stratified Randomized Phase lll Testing of blinatumomab (IND#117467, NCS#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL) |
Childhood Cancers |
Leukemia |
COG-ACNS0332 |
Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other than Average Risk Medulloblastoma/PNET Patients |
Childhood Cancers |
Blastoma |
COG-ACNS0831 |
Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 years |
Childhood Cancers |
Glioma |
COG-AEWS07B1 |
A Children's Oncology Group Protocol for Collecting and Banking Ewing Sarcoma Specimens |
Childhood Cancers |
Sarcoma |
COG-AHEP0731 |
Treatment of Children with All Stages of Hepatoblastoma |
Childhood Cancers |
Blastoma |
COG-AHOD1331 |
A randomized Phase III Study of Brentuximab Vedotin (SGN-35, IND # 117117) for Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents |
Childhood Cancers |
Lymphoma |
COG-ANBL00B1 |
Neuroblastoma Biology Studies |
Childhood Cancers |
Blastoma |
COG-AREN03B2 |
Renal Tumors Classification, Biology, and Banking Study |
Childhood Cancers |
Tumor |
COG: ARST1321 |
Pazopanib Neoadjuvant triao in Non-Rhabdomyosarcoma soft tissue sarcomas(PAZNTIS): A phase II/III randomized trial preoperative chemoradiation or preop radiation plus or minus Pazopanib |
Childhood Cancers |
Sarcoma |
COG:ACNS1123 |
Phase 2 trial of response based radiation therapy for patients with localized central nervous system Germ Cel Tumors |
Childhood Cancers |
Tumor |
Crest 2 |
The main purpose of the study is to find out if the incidence of stroke or death is different or the same between subjects that receive medical management alone compared to subjects that receive medical management in combination with carotid endarterectomy (CEA) or carotid artery stenting (CAS). |
Heart & Vascular |
Carotid Stenosis |
E4512 (sub study A151216) |
The purpose of this study is to compare Crizotinib vs observation for patients with a ALK+ Fusion Protein to determine if Crizotinib use results in improved disease-free survival. You must be diagnosed with stage 1B, stage 2 or stage 3A resectable or completely resected non-small cell lung cancer (NSCLC). |
Cancer |
Non-Small Lung |
EA3132 |
This study is comparing radiation therapy with and without Cisplatin. You must have surgically resected squamous cell carcinoma of the head and neck stage 3 or 4. |
Cancer |
Head and Neck |
EA3161 |
This study is comparing maintenance Nivolumab vs observation in patients with locally advance, intermediate risk HPV Positive oropharynx cancer. |
Cancer |
Oropharyngeal |
EA5163 |
The purpose of this study is to evaluate overall survival using immunotherapy alone or in combination with chemotherapy in advanced non-squamous Non-Small Cell Lung Cancer (NSCLC). You must be diagnosed with stage 4 Non-Small Cell Lung Cancer (NSCLC). |
Cancer |
Non-Small Cell Lung |
Improving Continuous Positive Airway |
Improving Continuous Positive Airway Pressure Adherence in Patients with Obstructive Sleep Apnea: Impact of Patient and Family Engagement (Improving CPAP Adherence |
Pulmonary |
Respiratory |
LUNGMAP |
This is a screening study to eavluate biomarker-driven therapies and immunotherapies in previously treated Non-Small Cell Lung Cancer (NSCLC). You must be diagnosed with Stage 4 or recurrent NSCLC. Tissue is sent for screening and patient can be assigned to a sub study based on mutations found. |
Cancer |
Metastatic Non-Small Cell Lung |
NRG-GI004 |
The purpose of this study is to look at the effectiveness of Atezolizumab alone or in combination with other chemo regimens. You must be diagnosed with metastatic colorectal cancer with a DNA mismatch repair deficiency and BRAF gene mutation. |
Cancer |
Metastatic Colorectal |
NRG-GI005 |
The purpose of this study is to look at the tumor DNA with blood draws to determine risk of cancer recurrance. You must be diagnosed with Stage 2A colon cancer. |
Cancer |
Colon |