S1706 |
This study is looking at using Olaparib after a masectomy at the same time as radiation vs getting radiation alone to determine if adding the medication provides better results. |
Cancer |
Breast |
S1803 |
The purpose of this study is to compare daratumumab and lenalidomide vs lenalidomide alone for maintenance therapy after stem cell transplant. You must be diagnosed with multiple myeloma. |
Cancer |
Multiple Myeloma |
S1806 |
The purpose to this study is to look at the effectiveness of adding atezolizumab to chemo and radiation. You must be diagnosed with muscle invasive bladder cancer. You cannot have already received chemo or radiation. |
Cancer |
Bladder |
S1900E (LUNGMAP sub study) |
The purpose of this study is determine if the use of Sotorasib is effective in patients with previously treated stage 4 or recuurent KRAS G12C mutated non-squamous non-small cell lung cancer (NSCLC). You must be diagnosed with NSCLC with a KRAS G12C mutation. |
Cancer |
Metastatic Non-Small Cell Lung |
S1914 |
This study is comparing the use of Atezolizumab + SBRT (stereotactic body radiation therapy) vs SBRT Alone in high risk early stage non-small cell lung cancer (NSCLC). You must be diagnosed with stage 1 or 2 non-small cell lung cancer (NSCLC). |
Cancer |
Non-Small Cell Lung |
S1922 |
The purpose of this study is to determine the effectiveness of Ramucirumab and Paclitaxel vs Folfiri chemo. You must be diagnosed with metastatic or unresectable small bowel cancer. |
Cancer |
Small Bowel |
S1925 |
The purpose of this study is to compare early intervention with Venetoclax and Obinutuzumab vs delayed therapy in newly diagnosed asymptomatic high0risk patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL). You must have been diagnosed with CLL or SLL within the last 12 months. |
Cancer |
Hematology |
S2001 |
The purpose of this study is to determine the effectiveness of Olaparib + Prembrolizumab vs Olaparib alone. You must be diagnosed with metastatic pancreatic cancer with a BRCA1 or BRCA2 mutation. |
Cancer |
Pancreatic |
S2013 |
The purpose of this study is the look at the side effects of immunotherapy treatment. You must be starting immunotherapy alone not in combination with other treatments. You must have a solid tumor. |
Cancer |
Solid Tumors |
S2107 |
The purpose of this study is to see if adding immunotherpy to chemo is more effective than chemo alone. You must be diagnosed with metastatic colorectal cancer. |
Cancer |
Metastatic Colorectal |
S2200 |
The purpose of this study is to compare treatment using cabozantinib with or without atezolizmab. You must be diagnosed with metastatic papillary renal cell cancer. |
Cancer |
Metastatic Renal Cell |
S2209 |
This study is for frail-intermediately fit newly diagnosed multiple myeloma patients. Your current lab values will be used to determine if you qualify for this study. This study compares different chemo regimens to determine the effectiveness of them. |
Cancer |
Multiple Myeloma |
S2212 |
The purpose of this study is to compare anthracycline-free, taxane-platinum chemo with pembrolizumab to taxane-platinum-anthracycline chemo with pembrolizumab. This study is for people diagnosed with triple negative breast cancer. |
Cancer |
Breast |
S2302 |
This study is comparing Ramucirumab + Pembrolizumab vs standard of care chemo for patients previously treated with immunotherapy. You must be diagnosed with stage 4 or recurrent Non-Small Cell Lung Cancer (NSCLC). |
Cancer |
Metastatic Non-Small Cell Lung |
SOUL Music |
This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with placement versus omission of a ureteral stent. Eligible participants in the randomization trial will be randomized to ureteroscopy with stent placement or stent omission. Eligible participants that consent to the observational only cohort will complete surveys and the treating physicians will decide the treatment options for the participants. |
Surgery |
Urinary Stone Disease |
Sync AV |
This is a new CRT with optimization turned on or off. |
Heart & Vascular |
Cardiac Arrhythmia |
Tandem |
The purpose of this study is to compare the effects of the study drug, obicetrapib when administered together with the drug ezetimibe as a fixed dose combination. A fixed dose combination means the two drugs are combined into a single tablet. The study will also check how safe obicetrapib and ezetimibe is for participants with high levels of LDL-C in the blood. |
Heart & Vascular |
Lipid Management; Cardiovascular Disease |
TAPUR |
The purpose of this study is find targeted treatment for patients with advanced cancer that has a actionable genomic variant revealed by genomic testing. Tissue from your cancer must be sent for genomic screening. You must have an advanced solid tumor, mulitple myeloma or B cell non-Hodgkin lymphona for which standard treatment options are no longer available. |
Cancer |
All tumor types |
URCC 18007 |
A study see if Bupropion is effective for reducing cancer-related fatigue. You must have completed surgery, radiation and/or IV chemo at least 2 months prior to enrollment. |
Cancer |
All tumor types |
V-Inception |
A randomized, controlled, multicenter, open-label trial comparing a hospital post-discharge care pathway involving aggressive LDL-C management that includes inclisiran with usual care versus usual care alone in patients with a recent acute coronary syndrome (VICTORION-INCEPTION) |
Heart & Vascular |
Lipid Management |