Search for Current Clinical Trials

Study Name Description Trial Category Trial SubCategory
POL6326-009 An International, Phase 3, Muticenter, Randomized, Open-Label Trial Comparing Balixafortide in combination with Eribulin versus Eribulin alone in Patients with HER2 negative, Locally Recurrent or Metastatic Breast Cancer Cancer Metastatic Breast
Portico NG This is a study of an updated Portico Valve for TAVR. Heart & Vascular Structural Heart Disease
Prominent Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes Heart & Vascular Lipid Management
Protected TAVR Stroke Protection with Sentinel During Transcatheter Aortic Valve Replacemen Heart & Vascular Structural Heart Disease
Radiance II The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication. Heart & Vascular Hypertension
RESILIENT A Randomized, Open Label Phase 3 Study of Irinotecan Liposome Injection (ONIVYDE®) versus Topotecan in Patients with Small Cell Lung Cancer Who Have Progressed on or after Platinum-based First-Line Therapy Cancer Lung
RTOG-0724 Phase III Randomized Study Of Concurrent Chemotherapy and Pelvic Radiation Therapy With Or Without Adjuvant Chemotherapy In High-Risk Patients With Early-Stage Cervical Carcinoma Following Radical Hysterectomy Cancer Gynecologic
S1602 A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG-Naïve High-Grade Non-Muscle Invasive Bladder Cancer Cancer Bladder, Genitourinary GU
S1608 Randomized Phase II Trial in Early Relapsing or Refractory Follicular Lymphoma Cancer Hematology
S1703 Randomized Non-Inferiority Trial Comparing Overall Survival of Patients Monitored with Serum Tumor Marker Directed Disease Monitoring (STMDDM) versus Usual Care in Patients with Metastatic Hormone Receptor Positive Breast Cancer Cancer Breast
S1706 A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer Cancer Breast
S1801 A Phase II Randomized Study of Adjuvant Versus NeoAdjuvant MK-3475 (Pembrolizumab) for Clinically Detectable Stage III-IV High-Risk Melanoma Cancer Melanoma
S1806 Phase III Randomized Trial of Concurrent Chemoradiotherapy with or without Atezolizumab in Localized Muscle Invasive Bladder Cancer Cancer Genitourinary GU
S1900A (LUNG-MAP Sub-Study) A Phase II Study of Rucaparib in Patients with Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-Small Cell Lung Cancer Cancer Lung
S1900B (LUNGMAP Sub-Study) A Phase II Study of LOXO-292 in Patients with RET Fusion-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer Cancer Lung
Sage The purpose of this study is to evaluate the efficacy and safety of brexanolone in participants on ventilator support for acute respiratory distress syndrome (ARDS) due to COVID-19. Internal Medicine Respiratory
Select This is a study of Selexipag in CTEPH (Chronic Thromboembolic Pulmonary Hypertension) Heart & Vascular Pulmonary Hypertension
SILVAR A Randomized, Double Blind, Controlled, Phase 3 Clinical Trial of Standard of Care with or without Siltuximab in Selected Hospitalized Patients with COVID-19 Previously Treated with Corticosteroids or Another Respiratory Virus Infection Associated with Acute Respiratory Distress Syndrome and Elevated C-Reactive Protein Levels. Internal Medicine Respiratory
Sync AV This is a new CRT with optimization turned on or off. Heart & Vascular Cardiac Arrhythmia
The TESLA Trial Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke Neurosciences Stoke
URCC 16070 Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer Cancer Breast
A011401 Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer Cancer Breast
A091304 A Phase I/Randomized Phase II Study of MLN0128 (TAK-228) vs. Pazopanib in Patients with Locally Advanced/Unresectable and/or Metastatic Sarcoma Cancer Sarcoma
A151216 (ALCHEMIST) Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST) Cancer Lung
Agendia FLEX The objective of this study is to create a large scale, population-based registry of full genome expression data and clinical data to investigate new gene associations with prognostic and/or predictive value Cancer Breast
E1Z11 (Only open for Asian patients) A Cohort Study to Evaluate Genetic Predictors for Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS) Cancer Breast
EA1131 A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy Vs. Capecitabine in Patients with Residual Triple-Negative Basal-Like Breast Cancer following Neoadjuvant Chemotherapy Cancer Breast
EA6134 A Randomized Phase III Trial of Dabrafenib + Trametinib Followed by Ipilimumab + Nivolumab at Progression vs. Ipilimumab + Nivolumab Followed by Dabrafenib + Trametinib at Progression in Patients With Advanced BRAFV600 Mutant Melanoma Cancer Melanoma
EA6141 Randomized Phase II/III Study of Nivolumab Plus Ipilimumab Plus Sargramostim Versus Nivolumab Plus Ipilimumab in Patients With Unresectable Stage III or Stage IV Melanoma Cancer Melanoma
EAY131 (MATCH) A Molecular Analysis for Therapy Choice (MATCH) - This study is a type of basket trial designed with the flexibility to open and close sub-protocols. Patients enrolled on study will have a tumor biopsy for molecular characterization and those with molecular variants addressed by treatments included in the trial will be offered treatment on MATCH. *Now using outside molecular reports which tumor must be collected within 6 months with no intervening treatment. Foundation One reports will now notify MATCH of molecular matches. Cancer Genomic testing based trial