Search for Current Clinical Trials

Study Name Description Trial Category Trial SubCategory
NRG-LU005: Limited Stage Small Cell Lung Cancer A Phase II/III Randomized Study of Chemoradiation VS Chemoradiation Plus Atezolizumab Cancer Lung
NRG-LU007 RAndomized Phase II/III Trial Of Consolidation Radiation + Immunotherapy for ES-SCLC: RAPTOR trial Cancer Lung
NSABP FB-12: An Open-Label Phase II Trial to Evaluate the Efficacy and Safety of Neoadjuvant Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel Plus Trastuzumab and Pertuzumab in Early Stage HER2-Negative Breast Cancer Patients Selected with a Test Measuring Live Cell HER2 Signaling Transduction (FACT 1) Cancer Breast
ON-TRK PrOspective Non-interventional study in patients with locally advanced or metastatic TRK fusion cancer treated with larotrectinib Cancer Genomic
OPUS A registry of patients taking Opsumit for pulmonary hypertension Heart & Vascular Hypertension
PFO Occulder (PAS) Amplatzer PFO Occluder Post Approval Study (No. SJM-CIP-10187 Ver. A) Heart & Vascular Structural Heart Disease
Portico NG This is a study of an updated Portico Valve for TAVR. Heart & Vascular Structural Heart Disease
Prominent Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes Heart & Vascular Lipid Management
Protected TAVR Stroke Protection with Sentinel During Transcatheter Aortic Valve Replacemen Heart & Vascular Structural Heart Disease
Radiance II The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication. Heart & Vascular Hypertension
RTOG-0724 Phase III Randomized Study Of Concurrent Chemotherapy and Pelvic Radiation Therapy With Or Without Adjuvant Chemotherapy In High-Risk Patients With Early-Stage Cervical Carcinoma Following Radical Hysterectomy Cancer Gynecologic
S1608 Randomized Phase II Trial in Early Relapsing or Refractory Follicular Lymphoma Cancer Hematology
S1703 Randomized Non-Inferiority Trial Comparing Overall Survival of Patients Monitored with Serum Tumor Marker Directed Disease Monitoring (STMDDM) versus Usual Care in Patients with Metastatic Hormone Receptor Positive Breast Cancer Cancer Breast
S1706 A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer Cancer Breast
S1801 A Phase II Randomized Study of Adjuvant Versus NeoAdjuvant MK-3475 (Pembrolizumab) for Clinically Detectable Stage III-IV High-Risk Melanoma Cancer Melanoma
S1806 Phase III Randomized Trial of Concurrent Chemoradiotherapy with or without Atezolizumab in Localized Muscle Invasive Bladder Cancer Cancer Genitourinary GU
Sage The purpose of this study is to evaluate the efficacy and safety of brexanolone in participants on ventilator support for acute respiratory distress syndrome (ARDS) due to COVID-19. Internal Medicine Respiratory
Select This is a study of Selexipag in CTEPH (Chronic Thromboembolic Pulmonary Hypertension) Heart & Vascular Pulmonary Hypertension
SILVAR A Randomized, Double Blind, Controlled, Phase 3 Clinical Trial of Standard of Care with or without Siltuximab in Selected Hospitalized Patients with COVID-19 Previously Treated with Corticosteroids or Another Respiratory Virus Infection Associated with Acute Respiratory Distress Syndrome and Elevated C-Reactive Protein Levels. Internal Medicine Respiratory
Sync AV This is a new CRT with optimization turned on or off. Heart & Vascular Cardiac Arrhythmia
The TESLA Trial Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke Neurosciences Stoke
URCC 16070 Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer Cancer Breast
A151216 (ALCHEMIST) Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST) Cancer Lung
Agendia FLEX The objective of this study is to create a large scale, population-based registry of full genome expression data and clinical data to investigate new gene associations with prognostic and/or predictive value Cancer Breast
EA6134 A Randomized Phase III Trial of Dabrafenib + Trametinib Followed by Ipilimumab + Nivolumab at Progression vs. Ipilimumab + Nivolumab Followed by Dabrafenib + Trametinib at Progression in Patients With Advanced BRAFV600 Mutant Melanoma Cancer Melanoma
EA6141 Randomized Phase II/III Study of Nivolumab Plus Ipilimumab Plus Sargramostim Versus Nivolumab Plus Ipilimumab in Patients With Unresectable Stage III or Stage IV Melanoma Cancer Melanoma
EAY131 (MATCH) A Molecular Analysis for Therapy Choice (MATCH) - This study is a type of basket trial designed with the flexibility to open and close sub-protocols. Patients enrolled on study will have a tumor biopsy for molecular characterization and those with molecular variants addressed by treatments included in the trial will be offered treatment on MATCH. *Now using outside molecular reports which tumor must be collected within 6 months with no intervening treatment. Foundation One reports will now notify MATCH of molecular matches. Cancer Genomic testing based trial
NRG BR003 A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer Cancer Breast
NRG-GU002 Phase II-III Trial of Adjuvant Radiotherapy Following Radical Prostatectomy With or Without Adjuvant Docetaxel Cancer Prostate
S0820 - Prevention of High-Risk Colorectal Polyps and New Colorectal Cancers PACES S0820 is a study to determine the efficacy of certain drugs in the prevention of high-risk colorectal polyps and new colorectal cancers in patients with previously treated colorectal cancer. Cancer Gastro-Intestinal