| Study Name | Description | Trial Category | Trial SubCategory |
|---|---|---|---|
| A011202 | A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy https://clinicaltrials.gov/ct2/show/NCT03797326?term=NCT03797326&draw=2&rank=1 | Cancer | Breast |
| A011801 | The CompassHER2 Trials (Comprehensive Use of Pathologic Response Assessment to Optimize Therapy in HER2-Positive Breast Cancer) CompassHER2 Residual Disease (RD), a Double-Blinded, Phase III Randomized Trial of T-DM1 Compared With T-DM1 and Tucatinib https://clinicaltrials.gov/ct2/show/NCT04457596?term=NCT04457596&draw=2&rank=1 | Cancer | Breast |
| A221805 | Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase II to Phase III Study https://clinicaltrials.gov/ct2/show/NCT04137107?term=NCT04137107&draw=2&rank=1 | Cancer | Gastrointestinal |
| ACCRU-BR-1801 | A Phase II Trial of Abemaciclib and T-DM1 in Women and Men with HER2 positive Advanced or Metastatic Breast Cancer Who Progressed on Treatment with a Taxane, Trastuzumab and Pertuzumab https://clinicaltrials.gov/ct2/show/NCT04351230?term=NCT04351230&draw=2&rank=1 | Cancer | Breast |
| EA2176 | A Randomized Phase III Study of Immune Checkpoint Inhibition with Chemotherapy in Treatment-Naïve Metastatic Anal Cancer Patients https://clinicaltrials.gov/ct2/show/NCT04444921?term=NCT04444921&draw=2&rank=1 | Cancer | Gastrointestinal |
| EA2187 | A Phase 2 Study of Penvonedistat in Combination with Carboplatin and Paclitaxel in Advanced Intrahepatic Cholangiocarcinoma https://clinicaltrials.gov/ct2/show/NCT04175912?term=NCT04175912&draw=2&rank=1 | Cancer | Gastrointestinal |
| NRG-GY009 | Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole Versus Letrozole Monotherapy in Patients with Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum https://clinicaltrials.gov/ct2/show/NCT03797326?term=NCT03797326&draw=2&rank=1 | Cancer | Other |
| S1613 | A randomized Phase II study of Trastuzumab and Pertuzumab (TP) compared to Cetuximab and Irinotecan (Cetiri) in advanced/metastatic colorectal cancer (MCRC) with Her-2 amplification https://clinicaltrials.gov/ct2/show/NCT03365882?term=S1613&draw=2&rank=1 | Cancer | Other |
| S1925 | S1925 Randomized, Phase III Study of Early Intervention with Venetoclax and Obinutuzumab Versus Delayed Therapy with Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study https://clinicaltrials.gov/ct2/show/NCT04269902?term=NCT04269902&draw=2&rank=1 | Cancer | Hematology |
| A DUE | Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) | Heart & Vascular | Pulmonary Hypertension |
| A021703 | Randomized Double-Blind Phase III Trial of Vitamin D3 Supplementation in Patients with Previously Untreated Metastatic Colorectal Cancer (SOLARIS) | Cancer | Gastrointestinal |
| A031501 | Phase III Randomized Adjuvant Study of MK-3475 (Pembrolizumab) in Muscle Invasive and Locally Advanced Urothelial Carcinoma (AMBASSADOR) Versus Observation | Cancer | Bladder/Urothelial |
| A031803 | Phase II Trial of Intravesical Gemcitabine and MK-3475 (pembrolizumab) in the Treatment of Patients with BCG-Unresponseve Non-Muscle Invasive Bladder Cancer | Cancer | Bladder |
| A041702 | Randomized Phase III Study of Ibrutinib Plus Obinutuzumab Versus Ibrutinib Plus Venetoclax and Obinutuzumab in Untreated Older Patients (= 70 Years of Age) | Cancer | Hematology |
| A061202 | A Phase I/II Study of Pomalidomide, Dexamethasone and Ixazomib VS. Pomalidomide and Dexamethasone for Patients with Multiple Myeloma Relapsing on Lenalidomide as Part of First Line Therapy | Cancer | Multiple Myeloma |
| AALL08B1 | Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) | Childhood Cancers | Leukemia |
| AALL0932 | Treatment of Patients with Newly Diagnosed Standard Risk B-Precursor Acute Lymphoblastic Leukemia (ALL) | Childhood Cancers | Leukemia |
| AALL1231 | A Phase lll Randomized Trial Investigating Bortezomib (NSC#681239; IND# 58443) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T-Lymphoblastic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LLy) | Childhood Cancers | Leukemia |
| AALL1521 | A Phase 2 study of the JAK1/JAK2 Inhibitor Ruxolitinib with Chemotherapy in Children with De Novo High-Risk CRLF2 Rearranged and/ or JAK Pathway-Mutant Acute Lymphoblastic Leukemia | Childhood Cancers | Leukemia |
| Acoustic Diagnosis of Gastroesophageal Reflux Disease | Baby/Child | Reflux Disease | |
| AIM Power | The goal of this real-world, multi-center, randomized, outpatient study is to assess the effectiveness of the Biofourmis cloud based BiovitalsHFTM Clinical Decision Support Platform to recommend optimal titration of Guideline-Directed Medical Therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) subjects. | Heart & Vascular | Heart Failure |
| ANBL1232 | Utilizing Response-and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High Risk Neuroblastoma | Childhood Cancers | Blastoma |
| Ant 004 | This is a study of a new anticoagulant vs. placebo in Afib. | Heart & Vascular | Atrial Fibrillation |
| ANT-004 / Azalea | Heart & Vascular | Atrial Fibrillation | |
| APEC14B1 EveryChild | A Registry, Eligibility Screening, Biology and Outcome Study | Childhood Cancers | Registry |
| Artesia | Apixaban for the Reduction of Thrombo-Embolism in Patients with Device-Detected Sub-Clinical Atrial Fibrillation | Heart & Vascular | Atrial Fibrillation |
| Champion AF | The primary objective of this study is to determine if left atrial appendage closure with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in patients with non-valvular atrial fibrillation. | Heart & Vascular | Atrial Fibrillation |
| COG-AALL05B1 | Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens | Childhood Cancers | Leukemia |
| COG-AALL1331 | Risk Stratified Randomized Phase lll Testing of blinatumomab (IND#117467, NCS#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL) | Childhood Cancers | Leukemia |
| COG-ACNS0332 | Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other than Average Risk Medulloblastoma/PNET Patients | Childhood Cancers | Blastoma |
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